PRISM is a non-profit, biomedical research institute focused on the development of innovative treatments for a wide spectrum of human diseases, including cancer. PRISM employs the principles of systems science, an ordered and interdisciplinary approach to study the relationships between healthy and diseased tissues. Located in San Diego, PRISM's state-of-the-art facilities combine advanced technologies in proteomics, genomics and in vivo imaging to discover and validate novel therapeutic targets.

PRISM develops novel molecules and probes which allow dynamic, non-invasive functional imaging of healthy and diseased tissue in vivo. These molecules and probes are the core component of new therapies, which specifically target diseased organs while sparing normal tissues and cells. In this way, PRISM is developing more effective, less toxic treatments that extend life and provide a better quality of life for patients diagnosed with chronic and life-threatening diseases.